Genetic Cancer Screening
Prevention. Precision.
Peace of mind.
At The Private Doctors, we believe your health deserves the most comprehensive insight possible. As part of our TPD Promise to deliver the most advanced and complete health screening services across Yorkshire, we offer Cancer Genetic Risk Testing - a detailed specific check of inherited cancer risk, integrated into our wider preventative health framework.
Genetic Cancer Screening - £950
PRIORITY & PRECISION
Why This Test Matters
HEREDITARY
CANCER RISK
Approximately 5–10% of cancers are hereditary, caused by genetic variants you inherit.
KNOWLEDGE IS POWER
Discovering a risk variant doesn’t mean you have cancer, but it provides a head start in early detection and prevention.
PERSONALISED PREVENTION
This knowledge lets us build a tailored screening and prevention plan—not generic advice.
GENERATIONAL IMPACT
Your results can guide screening for family members, allowing for proactive testing.
PRECISION
Which Genes are Analysed?
We analyse 31 clinically validated genes associated with inherited cancer risk.
These are among the most actionable, evidence-backed genes in clinical oncology and genetics.
Breast & ovarian
BRCA1, BRCA2, PALB2, BRIP1, RAD51C, RAD51D, ATM, CHEK2, BARD1
Colorectal & GI tract
APC, MLH1, MSH2, MSH6, PMS2, EPCAM, MUTYH, BMPR1A, SMAD4, POLE, POLD1, NTHL1, STK11
Prostate
HOXB13, BRCA1/2, ATM, CHEK2
Skin / melanoma
CDKN2A, CDK4, BAP1
Other associated cancers
TP53, PTEN, NF1, CDH1, VHL
We have chosen this targeted set deliberately — to maximise clinically actionable insight while minimising uncertain results.
HOW IT WORKS
Your Screening Journey
01
Pre Screening Consultation
You’ll complete a health & family history questionnaire before your sample appointment, helping us tailor your test.
02
Sample Collection
We collect a blood or saliva sample at our clinic in Leeds. The process is quick and comfortable.
03
Laboratory Analysis
Using next-generation sequencing, the 31 genes are analysed for variants known to confer cancer risk.
04
Reporting & Consultation
In 4–6 weeks, you’ll receive a detailed report and a one-to-one consultation with one of our doctors to go through your results.
05
Follow-up Pathway
If we identify a variant, we’ll help coordinate genetic counselling, tailored surveillance or preventive strategies, and family testing if needed.
What Your Results Mean
Positive / Pathogenic Variant
Meaning: You carry a gene variant that increases your cancer risk
What we do: Create a bespoke surveillance and prevention plan, counsel relatives
Negative / No Variant Detected
Meaning: No known high-risk variants found
What we do: You’re likely at general population risk, but we maintain general preventative care
Variant of Uncertain Significance (VUS)
Meaning: A change was detected, but its cancer risk is not yet known
What we do: We explain what’s known, monitor medical research and may reclassify later
EXCLUSIVE
The Private Doctors Promise.
This genetic screening forms part of our commitment to deliver the most comprehensive health screening service in Yorkshire.
At The Private Doctors, every screening is more than a checklist—it’s a precision-led, doctor-guided journey. Expect clarity, continuity, and care tailored to your individual risk.
Commonly Asked Questions
Who should consider this?
This test may be appropriate if you:
Are interested in a proactive, precision approach to your health, even without a strong family history.
Have a personal or family history of cancer (especially if diagnosed young).
Have had multiple cancers in the same family or rare tumour types.
How often do I need this?
You only need to do a genetic cancer screening test once, as your DNA doesn’t change. However, if new, more advanced panels become available in the future, or if your family history alters, we may recommend an updated test.
Does a positive result mean I have cancer?
No. It means you have a higher risk. We use that information to guide screening and prevention—not to alarm.
What if the result is negative?
It means no known high-risk variants were found. Your risk is likely similar to average population risk, but routine health monitoring still matters.
What is a VUS (Variant of Uncertain Significance)?
Sometimes we find a genetic change where its role in cancer risk is not clear. We will explain what is known and keep you informed as science develops.
How is the test performed?
With a simple blood or saliva sample taken at our clinic.
How long until I get results?
Typically 4 to 6 weeks from sample collection to report.
YOUR Health FUTURE STARTS TODAY
